TNFR2 Signaling Pathway
| PAG Title | TNFR2 Signaling Pathway |
| PAG ID | WIG000450 |
| Type | P |
| Source Link |  MSigDB |
| Publication Reference | NA |
| PAG Description | TNFR2 is the receptor for the 171 amino acid 19 kD TNF(beta) (a.k.a. lymphotoxin). TNF(beta) is produced by activated lymphocytes and can be cytotoxic to many tumor and other cells. In neutrophils, endothelial cells and osteoclasts TNF(beta) can lead to activation while in many other cell types it can lead to increased expression of MHC and adhesion molecules. |
| Species | Homo sapiens |
| nCoCo Score | 4,210 |
| Base PAG ID | WIG000450 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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